Searchable abstracts of presentations at key conferences in endocrinology

ea0034p323 | Reproduction | SFEBES2014

Interaction of androgen with IGF signalling in preantral follicle development in the mouse ovary

Jamall Hina , Laird Mhairi , Hardy Kate , Franks Stephen

Polycystic ovary syndrome (PCOS) is the commonest endocrine disorder in women of reproductive age. It is characterised by excessive ovarian androgen production which, in turn, has been implicated in the aetiology of aberrant follicular development. We have previously reported that prenatal exposure to androgens activates follicle growth1. It has been suggested that androgens may interact with the IGFs to promote the activation and growth of follicles. The aim of thi...